Murders always multiply when there's a full moon, Inspector Ricardo Ramirez knows. As he's investigating a vandal in the art world, a ghost appears by Ramirez's side... a sure sign that another murder victim is on the way. Ramirez's fears are confirmed when a dead prostitute is found in Havana with nylons wrapped tightly around her neck, an MO that connects to his only cold case. When another woman's body is discovered in a similar condition on a First Nation reserve in Northern Ontario, Detective Charlie Pike struggles to determine whether the murder is a standalone crime or if the Highway Strangler has struck again. Before long, both detectives find themselves tracking a killer whose reach extends further than they could have imagined.